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      PRF in Dentistry: What It Is (2026)

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      Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF)

      What Is PRF?

      Platelet-Rich Fibrin (PRF) is a treatment that uses a small sample of your own blood to promote healing after certain dental procedures. It may be used to support recovery of the gums, bone, or surgical site in suitable cases.

      It contains:

      • Platelets, which play a role in healing
      • Fibrin, a protein that forms a natural support structure
      • Growth factors, which may help with tissue repair
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      Once prepared, PRF is placed directly at the treatment site, such as an extraction socket, implant site, or surgical area. The fibrin acts like a natural scaffold that helps hold the material in place, while growth factors are released gradually at the treatment site. These may support the body’s natural healing response, including angiogenesis (formation of new blood vessels) and tissue repair.

      PRF is commonly used as an adjunct in procedures such as tooth extractions, dental implants, and selected gum or bone-related treatments. As it is made from your own blood, it is generally well tolerated and biocompatible. It may be considered in suitable cases where a more natural healing support approach is preferred. Its use will depend on your treatment plan and your dentist’s clinical judgment.

      PRF Treatment Benefits

      Potential benefits of PRF in dentistry include:

      • Supports wound healing: Forms a natural scaffold at the treatment site, which may help protect the area and support tissue repair after certain dental procedures
      • Supports soft tissue healing: May help create a more favourable environment for gum tissue recovery after selected grafting or periodontal treatments
      • Supports bone-related healing: May be used alongside procedures such as extractions, implants, or bone grafting to support healing in the surrounding area
      • Made from your own blood: Is generally well tolerated and biocompatible, which may make it a suitable option for patients who prefer a more natural healing support approach
      • Supports the body’s natural healing response: Contains platelets, fibrin, and growth factors that may help support tissue repair at the treatment site

      Your dentist will determine whether PRF is appropriate for your specific treatment. Not every dental procedure requires PRF, and outcomes can vary from person to person.

      PRF Uses In Dentistry

      • After tooth extraction: Your dentist may place PRF into the empty socket after removing a tooth. It may help the blood clot stabilise and support soft tissue healing in the area.
      • During dental implant treatment: PRF can be applied around the implant site to support bone and gum healing. Your dentist may use it at the time of placement or during follow-up procedures if needed.
      • With bone grafting: When bone graft material is used to rebuild lost bone, PRF may be mixed with the graft or placed over it. This may help the graft integrate with your existing bone.
      • In selected oral and maxillofacial surgery cases: PRF may be used as part of selected surgical procedures involving the mouth, jaws, or facial structures, where support for healing or tissue regeneration is needed.
      • In selected periodontal, implant, and regenerative procedures: PRF may be used in different forms, including injectable PRF (i-PRF), depending on how your dentist plans to support healing at the treatment site.

      Your dentist will advise whether PRF is suitable for your situation based on your treatment plan and oral health.

      Am I a Good Candidate for PRF?

      • Your dentist wants to support healing after a surgical dental procedure: This may be relevant if your treatment involves a healing site that could benefit from added support.
      • Your treatment involves bone or gum healing: PRF may be considered when your dentist wants to support recovery of hard or soft tissues.
      • Your dentist is planning a more involved procedure: In selected cases, PRF may be used as part of a broader surgical or regenerative treatment plan.
      • A more natural healing support approach is preferred: Because PRF is made from your own blood, it may be considered in cases where a biocompatible adjunct is preferred.

      PRF is not something you should self-diagnose or request without guidance. Your dentist will assess whether it may be appropriate for your situation.

      PRF Treatment Steps

      Before the Treatment

      • Your dentist will first assess whether PRF is suitable for your treatment. You should inform your dentist about any medications you are taking, particularly blood thinners, as these may affect the procedure.
      • Most patients do not need special preparation. You can eat and drink normally before your appointment. You do not need to fast or make dramatic changes to your routine beforehand.
      • Your dentist may ask about your medical history and current health status to ensure PRF is appropriate for your case. The treatment area will be examined and cleaned.
      • Your dentist will explain where the PRF will be placed and what to expect during the procedure. If you are having a tooth extraction or implant placement, PRF preparation will happen as part of that appointment.

      During the Treatment

      • A small blood sample is drawn from your arm, similar to a routine blood test. The amount is typically between 10 to 60 millilitres, depending on how much PRF is needed for your treatment.
      • Your blood is placed in sterile tubes and spun in a centrifuge machine. This spinning process separates your blood into layers.
      • The platelet-rich fibrin forms in the middle layer and is carefully collected by your dental team. The PRF appears as a yellowish gel or membrane.
      • Your dentist may use it in different forms depending on your treatment. It can be placed directly into a tooth socket after extraction, applied around a dental implant, or positioned over a bone graft.
      • No additives or chemicals are mixed with your blood. The entire process relies on your body's natural healing components.

      During the Treatment

      • You may experience normal post-treatment effects related to your dental procedure itself, such as mild swelling or discomfort. The PRF itself does not typically cause additional side effects since it comes from your own blood.
      • Follow your dentist's aftercare instructions carefully. These may include gentle cleaning around the treatment area, avoiding hard foods, and not disturbing the site with your tongue or fingers.
      • Most patients can resume normal activities the same day. Your dentist will schedule a follow-up appointment to monitor healing.
      • Contact your dental clinic if you notice unusual pain, persistent bleeding, or signs of infection.

      PRF Risks

      • Temporary swelling: May occur around the treatment area after the procedure
      • Soreness: Mild tenderness can happen depending on the dental procedure performed
      • Bruising: May appear at the blood draw site or treatment area and usually fades within a few days

      These effects are usually mild and short-lived. Before proceeding, your dentist will review your medical history and discuss whether PRF is suitable for your treatment. If you have any medical conditions or take regular medication, let your dentist know in advance.

      PRF Complications

      • Persistent discomfort: Pain or tenderness that does not settle as expected
      • Delayed healing: Recovery may take longer in some cases
      • Bruising at the blood draw site: Occasionally more noticeable or longer-lasting

      It is important to remember that PRF is usually used alongside a broader dental procedure, such as an extraction, implant placement, or grafting treatment. This means some complications may be related to the main procedure rather than PRF alone. If you notice unusual or worsening symptoms after treatment, contact your dental clinic for advice.

      Cost of PRF Treatment in Singapore

      PRF is usually charged as an add-on to your main dental procedure rather than as a standalone treatment. As a general guide, it may add about SGD $250 to SGD $900 to the overall cost, depending on the procedure, case complexity, and whether grafting or surgery is involved. Exact pricing varies by clinic, so your dentist will advise you based on your treatment plan.

      Are There Subsidies for PRF Treatment in Singapore?

      PRF is usually treated as an add-on to the main dental procedure, so it is not typically claimable on its own. Whether any subsidy or MediSave claim applies usually depends on the underlying procedure, the care setting, and your eligibility. In Singapore, CHAS subsidies apply to eligible Singapore Citizens at participating clinics, while MediSave is generally used for qualifying surgical dental procedures such as dental implant insertion or removal rather than non-surgical dental treatment. Check with your clinic for a case-specific breakdown before proceeding.

      How Nuffield Dental Can Help With PRF

      • Clinicians with biological dentistry credentials: Nuffield Dental includes dentists with formal biological dentistry-related credentials. For example, Dr. Surinder Arora is a Board Certified Biological Dentist accredited by the IABDM and is SMART certified by the IAOMT.
      • Structured nurse training and in-house staff development: Nuffield Dental conducts official staff training 4 times a year, with additional in-house training led by senior nurses to support consistent surgical assistance and patient care standards.
      • Training and education in PRF: Nuffield’s broader dental ecosystem also includes training on PRF and PRP through Nuffield Academy, covering topics such as implant applications, preparation, and when these techniques may be used in practice.

      Aftercare After a PRF Treatment

      • Immediate care (first 6 hours): Do not touch, rub, or press on the treated area. Avoid rinsing your mouth forcefully or using mouthwash. If PRF was placed after an extraction or graft, handle the area especially gently.
      • First 24 to 48 hours: Avoid strenuous exercise, heavy lifting, and very hot foods or drinks. Do not smoke or use tobacco products. If you have swelling, sleeping with your head slightly elevated may help.
      • Days 2 to 7: Keep the area clean by brushing gently around the site. Follow any cleaning or rinsing instructions given by your dentist. Continue avoiding vigorous activity for at least 3 days, or longer if advised.
      • What you may notice: Mild swelling or discomfort can happen after dental surgery, whether PRF is used or not. These symptoms should gradually improve over the next few days.
      • When to contact your dentist: Seek advice if you notice increasing pain, significant swelling, or bleeding that does not stop.
      • Follow-up visits: Your dentist may arrange a review appointment to monitor healing. Improvement is often seen within 2 to 4 weeks, though full healing may take longer depending on the procedure.

      PRF (Platelet-Rich Fibrin) Vs PRP (Platelet-Rich Plasma)

      Comparison Point Platelet-Rich Fibrin (PRF) Platelet-Rich Plasma (PRP)
      Preparation Usually prepared without anticoagulants and is often made using single centrifugation Usually prepared using anticoagulants and typically involves double centrifugation
      Physical form Fibrin clot or membrane-like Liquid or plasma-like
      Fibrin structure Contains a fibrin matrix that acts as a natural scaffold Less of a natural fibrin scaffold
      Growth factor release Tends to provide a more gradual, sustained release of growth factors over time Tends to release growth factors more quickly at earlier time points
      Leukocytes Generally higher leukocyte content in many PRF preparations Lower or more variable leukocyte content, depending on the protocol
      How it is often used in dentistry Often used when a scaffold and more sustained release may be helpful, such as in extractions, grafting, or implant-related procedures May be chosen when a quicker delivery of growth factors is desired

      Our Team of Dentists Behind PRF

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      At Nuffield Dental clinic, your dental needs are cared for by our dedicated team of dentists.

      Dr Faisal Bin Abdul Aziz

      Specialisation

      General Dentistry

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      BDS (London)

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      Dr Steffi Soh Yu Hui

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      General Dentistry

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      BDS (Adelaide)

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      Dr Narinder Kaur

      Specialisation

      General Dentistry

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      BDS (Singapore)

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      Dr Seetoh Yu Fang

      Specialisation

      General Dentistry

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      BDS (Adelaide)

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      Dr Lim Mei Xian

      Specialisation

      General Dentistry

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      BDS (New Zealand)

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      Dr Bruce Lee Ziahern

      Specialisation

      General Dentistry

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      BDS (UK)

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      Dr Loughran Peter Joseph

      Specialisation

      General Dentistry

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      BDS (UK)

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      Dr Lee An Qi

      Specialisation

      General Dentistry

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      BDS (Singapore)

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      Dr Annaajihah

      Specialisation

      General Dentistry

      Training

      BDS (Adelaide)

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      Dr Tho Loo Yee

      Specialisation

      General Dentistry

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      BDS (Singapore)

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      Dr Hanna Aslam

      Specialisation

      General Dentistry

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      BDS (UK)

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      Dr Lai Juen Bin

      Specialisation

      General Dentistry

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      BDS (Singapore)

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      Dr Tiju Krishnan

      Specialisation

      General Dentistry

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      BDS (Glasgow)

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      Dr Wu Shilin Serene

      Specialisation

      General Dentistry

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      BDS (Singapore)

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      OHT Rebecca Siow Hui Lin

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      Diploma in Oral Health (NYP)

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      Dr Anusha Chopra

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      FAQs

      Is PRF safe to use in dentistry?

      PRF is generally considered safe in dentistry because it is made from your own blood, which lowers the risk of rejection or disease transmission. It is usually used as an adjunct, with suitability assessed by your dentis

      What role does PRF play in periodontics?

      In periodontics, PRF is used as an adjunct to support gum and periodontal tissue healing. It may help create a more favourable environment for soft tissue repair and periodontal regeneration in selected cases.

      Does PRF guarantee faster healing after dental treatment?

      PRF may support healing, but it does not guarantee faster recovery. Each patient heals at their own pace. Factors like your overall health, oral hygiene, and the complexity of your procedure all play a role. Your dentist may use PRF to help improve conditions for healing. You should still follow all post-treatment care instructions.

      Can PRF replace bone grafting or other parts of dental treatment?

      PRF cannot replace bone grafts in most cases. It is used alongside other treatments to support healing and tissue regeneration. Your dentist will recommend the appropriate combination of procedures based on your specific needs.

      Will I need more than one PRF application?

      Most dental procedures use PRF once during the treatment. In some cases, your dentist may recommend additional applications if needed. This depends on the type of procedure and how your body responds.

      How long does a PRF-related dental procedure usually take?

      The blood draw and preparation add about 10 to 15 minutes to your appointment. The overall time depends on the main procedure being performed. Your dentist will explain the full timeline during your consultation.

      Is PRF suited for all ages?

      PRF is not usually limited to a specific age group in dentistry. Your dentist will consider the procedure, healing needs, and your overall suitability before deciding whether PRF is appropriate.

      Medical References

      Acerra, A., Caggiano, M., Chiacchio, A., Scognamiglio, B., & D’Ambrosio, F. (2025). PRF and PRP in dentistry: an umbrella review. Journal of Clinical Medicine, 14(9), 3224.

      Borie, E., Oliví, D. G., Orsi, I. A., Garlet, K., Weber, B., Beltrán, V., & Fuentes, R. (2015). Platelet-rich fibrin application in dentistry: a literature review. International journal of clinical and experimental medicine, 8(5), 7922.

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      Cost Of Root Canal Treatment In Singapore

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      Cost Of Root Canal Treatment In Singapore

      Root Canal Treatment Cost

      The price varies according to the unique treatment prescribed to each individual patient. For example, if a root canal treatment is require for more than one root, the cost would go up as well. However, saving the tooth with a Root Canal treatment is relatively cost-efficient in the long run. 

       

      A Root Canal Treatment procedure in Singapore's price ranges from S$500 - S$1700. However, the price may or may not include the crowning of the tooth and consultation charges. Average consultation prices of dental services in Singapore ranges from S$75- S$200. 

      Read More

      Root Canal Treatment FAQs

      Is a Root Canal Treatment procedure painful?

       

      • The entire procedure will be done under local anaesthesia, so it will not be painful than getting your tooth filled or a wisdom tooth surgery. However, the affected area may cause discomfort and be slightly sore post-surgery but it goes away after a few days. 
      • If the pain persists, please consult our doctor immediately. You can reach us at +65 9839 7363.

        Can I go about my day to day activities after a Root Canal Treatment? 

      • Most patients are able to return to school or work the next day following a Root Canal Treatment. However, it is advised against eating immediately post-surgery as there may be numbness in the affected area. 

      What are the side effects of a Root Canal Treatment?

      • The side effects of a Root Canal Treatment differs with each individual. Some people may experience pain or a slight soreness post-surgery, and some people may experience little to no pain at all. This also applies to certain patients experiencing a measured amount of sensitivity associated to cold or heat when consuming food or beverages. 

      What is the aftercare for a Root Canal Treatment? 

       

      • As a Root Canal Treatment is considered a restorative procedure, the after-care is deemed crucial to experience lasting effects. After your procedure, your dentist will send you home with pain-killers to counter the soreness you may feel when the anaesthesia wears off. It is also strongly advised against the consumption of food until the numbness wears off. Brushing and flossing daily is encouraged to keep the area clean and this in turn would prevent infection. Upon completing any follow-up appointments for the Root Canal Treatment, you may be required to return to the dentist for a final crown to fully restore the tooth. A properly treated and restored tooth can last as long as your natural teeth. 

      Can a Root Canal Treatment be unsuccessful? 

       

      • A Root Canal Treatment has a 90% success rate of fully restoring your tooth. However. failure to fully restore your tooth can occur if there is a loose crown, tooth fracture or decay. Undetected canal branches or an obstruction that causes the cleaning difficulties may also cause a Root Canal Procedure to fail. Should your Root Canal Treatment be unsuccessful, explore options with Nuffield's Endodontist for possible solutions. 

       

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      Nuffield Dental is a one-stop, multi-disciplinary dental care centre. Here at Nuffield Dental, we pride ourselves of our personalised oral care for each and every one of our patients. We need to make sure you get all the help you need to make your dental procedures comfortable, accessible and seamless.

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